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Table 1 Comparison of pain, nausea and vomiting and number and dose of painkiller administration in the intervention and control groups during the study period

From: The effect of lemon inhalation aromatherapy on pain, nausea, as well as vomiting and neurovascular assessment in patients for lower extremity fracture surgery: a randomized trial

Variables

Times

Groups

Test, p-value

Intervention Mean (SD)

Control Mean (SD)

Pain intensity

Before the intervention

5.28 (0.94)

5.60 (1.26)

F = 1.88, p = 0.17a

Entering recovery room

2.75 (2.99)

3.35 (3.17)

F = 4.45, p = 0.03b

4 h after entering the ward

6.42 (1.11)

6.97 (1.19)

F = 5.43, p = 0.02c

8 h after entering the ward

6.46 (0.91)

6.64 (0.98)

F = 1.16, p = 0.28c

12 h after entering the ward

6.20 (0.91)

6.73 (1.13)

F = 6.49, P = 0.01c

16 h after entering the ward

4.91 (0.82)

6.24 (0.88)

F = 65.88, p < 0.001c

Between groups ANCOVA repeated measure

F = 23.89, p < 0.001c

Number of painkiller administration

24 h before the intervention

1.82 (0.64)

1.73 (0.57)

t =—0.68, p = 0.49

In the recovery room

0.46 (0.69)

0.44 (0.62)

t =—0.16, p = 0.87

16 h after surgery and in the ward

2.80 (0.54)

2.60 (0.53)

t =—1.74, p = 0.08

Between groups repeated measure

F = 1.60, p = 0.20

Dose of pethidine administration

16 h after surgery and in the ward

27.29 (7.22)

30.15 (10.11)

t =—1.36, p = 0.17

Nausea and vomiting intensity

Before the intervention

–––––

–––––

––––

Entering recovery room

0 (0.0)

5.75 (0.95)

F = 5.06, p = 0.02d

4 h after entering the ward

0.11 (0.55)

1.45 (2.31)

F = 7.92, 0.006e

8 h after entering the ward

0 (0.0)

0.54 (1.82)

F = 0.72, 0.39e

12 h after entering the ward

0 (0.0)

0.06 (0.45)

F = 0.07, 0.78e

16 h after entering the ward

0 (0.0)

0.04 (0.30)

F = 0.07, 0.78e

Between groups ANCOVA repeated measure

F = 12.94, p = 0.001

  1. aThe use of analgesics during last 24 h, and the site of fracture as covariates
  2. bThe type of anesthesia, the use of analgesics in pre-intra operative, and the site of fracture as covariates
  3. cThe type of anesthesia, the use of analgesics in pre-intra and postoperative, and the site of fracture as covariates
  4. dThe type of anesthesia and site of fracture as covariates
  5. eThe type of anesthesia, site of fracture, and the use or non-use of anti-emetic drugs in vomiting in recovery and in the postoperative ward as covariates