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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Butyrate inhibits the mitochondrial complex Ι to mediate mitochondria-dependent apoptosis of cervical cancer cells

Fig. 6

Butyrate-induced mitochondrial-dependent apoptosis by inhibition of the mitochondrial complex Ι in CC cells. (A) Heat map analysis of changes in energy metabolism between the CON group and the NaB group. (C) Levels of mitochondrial NADH and NAD + in CC cells. (B) RT-qPCR analysis of related mRNA expression in the CON group and the NaB group. (E) Detection of mitochondrial membrane potential by JC-1 flow cytometry. (D) Quantitative analysis of the JC-1 fluorescence ratio in HeLa cells treated with 5mM butyrate for 12, 24 and 48 h. CON: Control group. NaB: Group treated with 5mM butyrate for 48 h. Data were expressed as the mean ± SD. * P < 0.05

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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