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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Butyrate inhibits the mitochondrial complex Ι to mediate mitochondria-dependent apoptosis of cervical cancer cells

Fig. 4

Butyrate activated the mitochondrial-dependent apoptosis pathway in CC cells. Western blot analysis of (A) Caspase 8, 9, 12, (D) Apaf-1, Bcl-2 and Bax. (B, E) Quantitative analysis of Western blot in the CON and NaB groups. (G) Comparison of the Bax/Bcl-2 protein ratio between the CON group and the NaB group. (C) Cytc immunofluorescence staining in the CON and NaB groups. (F) Immunofluorescence for ROS. (H) Flow cytometry for quantitative detection of ROS. CON: Control group. NaB: Group treated with 5mM butyrate for 48 h. Data were expressed as meas ± SD. ** P < 0.01

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BMC Complementary Medicine and Therapies

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