Table 2 Measurement items and assessment of study endpoints

Follow-up times

1

2

3

4

5

6

Time point

0 Day

24 h

48 h

72 h

96 h

120 h

Case screening

History

√

Indicator check

√

√

√

Basic information

√

Determine the inclusion

√

Informed content

√

Indicator check

Temperature

√

√

√

√

√

√

BP/HR/P/symptoms/signs

√

√

√

√

√

√

Blood routine/Urine routine

√

√

Liver function/Kidney function

√

√

Twelve-lead ECG

√

√

Pathogen test

√

√

Inflammatory factor test

√

√

Others

randomization

√

Drug distribution

√

Drug recycle/

medication compliance

√

Combined medication

√

√

√

√

√

AEs

√

√

√

√

√

Recycle drug

√

Conclusion of Completion of experiment

√