Fig. 2
From: Therapeutic efficacy of sorafenib and plant-derived phytochemicals in human colorectal cancer cells
Sequence-dependent antiproliferative effects of the combined treatment of Sora and Cur on (A) SW1116 and (B) SW837 human colorectal cancer cell lines. Cells were treated with a combination of Sora (0–10 μM) and Cur (60 and 120 μM) in (a) sequential, (b) inverted sequential or (c) simultaneous manners. Cell growth was analysed using the MTT assay. (Aa) SW1116, sequential treatment [Sora + Cur (120 µM)] vs. Sora, *P < 0.05. (Bb) SW837, inverted sequential treatment [Sora + Cur (120 µM)] vs. Sora, **P < 0.05. (Bc) SW837, simultaneous treatment [Sora vs. Sora + Cur (60 µM) or Sora + Cur (120 µM)], ***P < 0.05. Sora, sorafenib; Cur, curcumin