Fig. 10

Flow cytometric analysis of apoptosis in human rectum cancer cell line SW837 treated with Sora, Cur, or Kmf and a combination of both. SW837 was untreated (a), treated with Sora (5 µM) (b), Cur (200 µM) (c), Cur (400 µM) (d), and sequential treatments of Sora (5 µM) and Cur (200 or 400 µM) (e, f) or treated Kmf (200 µM) (g), Kmf (400 µM) (h), and sequential treatments of Sora (5 µM) and Kmf (200 or 400 µM) (i, j) for 72 h. B1, percentage of necrotic cells; B2, percentage of late apoptotic cells; B3, percentage of viable cells; and B4, percentage of early apoptotic cells. Sora, sorafenib; Que, quercetin; Kmf, kaempherol; UT, untreated; PI, propidium iodide; FITC, fluorescein isothiocyanate; CRC, colorectal cancer