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Table 2 Effect of PA on the content of fibrosis indicators in renal of SHR rats

From: 2-phenylacetamide Separated from the seed of Lepidium apetalum Willd. inhibited renal fibrosis via MAPK pathway mediated RAAS and oxidative stress in SHR Rats

Groups

TGF-β

(pg/mL)

FN

(pg/mL)

WKY

1548.55 ± 177.22

275.76 ± 34.74

SHR

3705.17 ± 516.48**

480.41 ± 33.72**

SHR + HCTZ

3244.71 ± 51.03

400.04 ± 25.42

SHR + 15

2750.08 ± 337.07##

440.75 ± 19.25

SHR + 30

2629.00 ± 511.91##

417.86 ± 71.80

SHR + 45

2549.39 ± 300.90##

407.58 ± 51.70#

  1. Data are expressed as mean ± SD, n = 8 per group. * P < 0.05, ** P < 0.01 vs. WKY group; # P < 0.05, ## P < 0.01 vs. SHR group
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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