Fig. 4

THF-H promoted mitochondrial energy metabolism-related mRNA expression in epididymal white adipose tissue of HFD/STZ-induced T2DM mice. A-B mRNA expression of AMPKα and AMPK. C-D mRNA expression of MCU and MICU1. E–F mRNA expression of SIRT1 and PGC-1α. G-L mRNA expression of COX4, TFAM, UQCRb, NDUFS8, SDHb and COX5b. Notes:^*P < 0.05, ^**P < 0.01, ^***P < 0.001 vs Control, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs Model. All the data were presented as the means ± SEMs (n = 4–6)