Fig. 3

THF-treated mice exhibited improved mitochondrial structure. A Representative images of H&E-stained Bat of T2DM mice. B Representative images of H&E-stained epididymal E-Wat of T2DM mice. C Representative images of electron microscopy of E-Wat. D Oxygen consumption (VO₂). E Carbon dioxide (VCO₂). F-G VCO₂/VO₂ and AUC analysis of VCO₂/VO₂. H Mitochondrial Ca²⁺ levels of E-Wat. I Mitochondrial membrane potential MMP levels of E-Wat. J Relative ATP levels of E-Wat. Notes:^*P < 0.05, ^**P < 0.01, ^***P < 0.001 vs Control, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs Model. All the data were presented as the means ± SEMs (n = 6–8). Scale: 50 μm