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Table 5 Cell population content (%) found in early apoptosis, late apoptosis, necrosis, and live cells caused by PSS, PL, and cisplatin exposure 4 breast cancer cell lines

From: Effect of Smilax spp. and Phellinus linteus combination on cytotoxicity and cell proliferation of breast cancer cells

Breast cancer cell line

Cell population (Mean (%) ± SE)

Viable cells

Early Apoptotic cells

Late Apoptotic cells

Necrotic cells

MCF7

 - Untreated

87.74 ± 5.12

2.53 ± 0.81

22.41 ± 0.80

0.57 ± 0.22

 - PSS

78.72 ± 7.34

2.55 ± 0.48

31.66 ± 6.74

0.70 ± 0.35

 - PL

75.59 ± 4.70

6.52 ± 0.47 **

27.77 ± 5.05

0.32 ± 0.15

 - Cisplatin

54.78 ± 4.65 ***

23.76 ± 3.76 ***

30.56 ± 11.09

1.41 ± 0.44

T47D

 - Untreated

96.06 ± 1.81

1.39 ± 0.40

3.24 ± 1.30

0.24 ± 0.09

 - PSS

91.06 ± 0.62 *

1.67 ± 0.09

6.56 ± 0.52 *

0.71 ± 0.07 **

 - PL

83.57 ± 1.38 ***

4.55 ± 0.28 ****

11.24 ± 1.24 ***

0.65 ± 0.04 **

 - Cisplatin

52.18 ± 2.88 ****

33.26 ± 2.20 ****

13.73 ± 0.70 ****

0.82 ± 0.21 *

MDA-MB-231

 - Untreated

96.65 ± 1.34

0.93 ± 0.29

2.16 ± 0.99

0.26 ± 0.07

 - PSS

87.99 ± 1.63 **

1.87 ± 0.13 *

8.95 ± 1.19 **

1.19 ± 0.37 *

 - PL

89.21 ± 1.20 **

1.80 ± 0.05 *

7.70 ± 0.86 **

1.30 ± 0.47

 - Cisplatin

70.22 ± 3.49 ****

11.87 ± 1.38 ****

15.99 ± 2.23 ***

1.92 ± 0.64 *

MDA-MB-468

 - Untreated

99.08 ± 0.11

0.56 ± 0.03

0.28 ± 0.07

0.28 ± 0.19

 - PSS

88.01 ± 1.41 ****

3.17 ± 0.54 ***

8.33 ± 1.23 ****

0.24 ± 0.05

 - PL

90.11 ± 1.26 ****

2.90 ± 0.32 ****

6.80 ± 1.12 ***

0.23 ± 0.04

 - Cisplatin

43.64 ± 5.69 ****

34.81 ± 5.04 ****

20.40 ± 1.89 ****

1.19 ± 0.28

  1. *, **, ***, **** represented P ≤ 0.05, P ≤ 0.01, P ≤ 0.001, and P ≤ 0.0001 from statistical analysis using Unpaired t-test