Catechin, epicatechin, curcumin, garlic, pomegranate peel and neem extracts of Indian origin showed enhanced anti-inflammatory potential in human primary acute and chronic wound derived fibroblasts by decreasing TGF-β and TNF-α expression

Table 2 Percentage cell viability of HDF cell line treated with various concentrations of phytoextracts

Test phytoextracts	Cell viability (%)
	Untreated (control)	Concentration of test phytoextracts
	Untreated (control)	25 μg/ml	50 μg/ml	100 μg/ml	200 μg/ml	400 μg/ml
CE	100 ± 00	97.93 ± 0.62 **	97.26 ± 0.47 ***	94.82 ± 0.09 ***	87.85 ± 0.27 ***	79.65 ± 0.08 ***
E	100 ± 00	97.29 ± 0.69 **	94.62 ± 0.09 ***	91.52 ± 0.10 ***	85.26 ± 0.09 ***	74.99 ± 0.79 ***
CU	100 ± 00	99.4 ± 0.14	97.22 ± 0.63 **	91.68 ± 0.12 ***	84.36 ± 0.68 ***	65.08 ± 0.66 ***
G	100 ± 00	97.22 ± 0.93*	94.13 ± 0.54 ***	89.88 ± 0.51 ***	86.14 ± 0.14 ***	79.26 ± 0.86 ***
P	100 ± 00	97.95 ± 1.09	94.45 ± 1.13 ***	87.35 ± 0.27 ***	79.91 ± 0.53 ***	54.86 ± 0.73 ***
N	100 ± 00	97.05 ± 0.73*	95.07 ± 0.81 ***	90.08 ± 0.45 ***	71.08 ± 0.83 ***	48.23 ± 0.49 ***

Values are expressed as the mean ± SEM (n = 3); Statistical significance (P) calculated by one-way ANOVA followed by Dunnett’s test— ***P < 0.001, **P < 0.01, *P < 0.05 were considered as statistically significant by comparing treated group with control group

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