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Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: Catechin, epicatechin, curcumin, garlic, pomegranate peel and neem extracts of Indian origin showed enhanced anti-inflammatory potential in human primary acute and chronic wound derived fibroblasts by decreasing TGF-β and TNF-α expression

Fig. 8

TGF-β expression histogram of test phytoextracts against CWFs (a) TNF-α expression histogram of test phytoextracts against CWFs (b). Note: A- HDF control, B- CWF Untreated, C- Catechin extract, D- Epicatechin extract, E- Curcumin extract, F- Garlic extract, G- Pomegranate extract, H- Neem Extract. TGF-β histogram of the gated CWF singlets distinguishes cells at the M1 and M2 phases. (Here M1 refers to negative expression/region and M2 refers to the Positive expression/region). Gating of M1 and M2 phases is approximate and can be refined using software (Cell Quest Pro Software, Version 6.0) analysis. % of cells observed in M2 region is considered as TGF- β expression

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