Fig. 3

Effects of PSC-FEs on the expression of (A) insulin receptor, (B) GLUT1 and (C) GLUT4 in insulin-resistant HepG2 cells. The insulin-resistant HepG2 cells were treated with 50 ug/ml of total and methanolic PSC-FEs and used for RNA extraction 24 h after treatment. Total RNA was reverse transcribed and used a template in quantitative real-time PCR. Treatment with 1 mM metformin was considered as positive control. Data represent mean ± SD from three individual experiments performed in triplicate. ** p < 0.01 and *** p < 0.001 compared with untreated insulin-resistant cells (model). ## p < 0.01 and ### p < 0.001 compared with untreated HepG2 cells (control)