Fig. 4From: Neuroprotective effects of morroniside from Cornus officinalis sieb. Et zucc against Parkinson’s disease via inhibiting oxidative stress and ferroptosisEffect of morroniside on oxidative stress in PC12 cells. (A) Effect of morroniside on the viability of PC12 cells by CCK-8. (B) Effect of morroniside or ML385 on the viability of PC12 cells by CCK-8. (C) GSH and MDA in PC12 cells through Elisa. (D) mRNA levels of GPX4 and SLC7A11. (E) Effect of morroniside or ML385 on ROS in PC12 cells using Flow Cytometry. (F) Levels of Nrf2 and HO-1 in PC12 cells by Western blot. (G) Relative expression of Nrf2 and HO-1. Data are shown as mean values ± SD, n = 3 per group, *p < 0.05, ns indicates p ≥ 0.05Back to article page