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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Neuroprotective effects of morroniside from Cornus officinalis sieb. Et zucc against Parkinson’s disease via inhibiting oxidative stress and ferroptosis

Fig. 3

Morroniside regulates ferroptosis in the substantia nigra cells. (A) Prussian blue iron staining of the substantia nigra. (B) Ferrous iron in substantia nigra. (C) Relative expression of Nrf2. (D) Immunofluorescence for the detection of Nrf2. (E) Levels of GSH and MDA in substantia nigra. (F) Relative mRNA expression of GPX4 and SLC7A11 using qRT-PCR. (G) HO-1, GPX4, SLC7A11, FTH-1, and FPN in substantia nigra by Western blot. (H) Relative expression of HO-1, GPX4, SLC7A11, FTH-1, and FPN. Data are shown as mean values ± SD, n = 6 per group, *p < 0.05, **p < 0.01, ***p < 0.001

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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