Fig. 3

A Visible separation was not identified clearly between the two groups from the score plot of principal component analysis (PCA). B Partial least-squares determinant analysis (PLS-DA) showed a complete separation of detected ions in parthenolide treated groups from control groups [R2X (cum) = 0.384, R2Y (cum) = 0.907, Q2 (cum) = 0.44]. C Orthogonal projections to latent structures discriminant analysis (OPLS-DA) showed a complete separation of detected ions in parthenolide treated groups from control groups [R2X (cum) = 0.384, R2Y (cum) = 0.907, Q2 (cum) = 0.509]. D Permutation test of the PLS-DA model [Q2-intercept = -0.7946]. E Permutation test of the OPLS-DA model [Q2-intercept = -0.3653]