Fig. 2

Effects of XYS on depressive-like behaviors of rats (A) Behavioral track heatmap of rats in the OFT. (B) Total distance traveled in the OFT. (C) Time spent in the center of the OFT. (D) Sucrose preference in the SPT before and after establishing CUMS modeling. (E) Immobility time in the FST. Data are presented as mean and standard deviation. n = 10, 10–14, 11–14 per group in OFT, SPT and FST, respectively; *P < 0.05, **P < 0.01, vs. control group; ^#P < 0.05, ^##P < 0.01, vs. model group. XYS, Xiaoyaosan; OFT, open field test; SPT, sucrose preference test; FST, forced swim test; CUMS, chronic unpredictable mild stress