Table 3 Docking scores (kcal/mol) of TNF-α, IFN-γ and IL-1β with the isolated compounds and the reference anti-inflammatory drug (piroxicam)
|  | TNF-α (2AZ5) | IFN-γ (6E3K) | IL-1β (4DEP) |
|---|---|---|---|
Compound 1 Alternariol monomethyl ether | -7.648 | -4.682 | -2.830 |
Compound 2 3’-Hydroxyalternariol monomethyl ether | -6.274 | -5.242 | -4.452 |
Compound 3 Alternariol | -6.414 | -4.246 | -3.788 |
Compound 4 α-Acetylorcinol | -5.054 | -3.989 | -2.931 |
Compound 5 Tenuazonic acid | -4.593 | -2.845 | -3.121 |
Compound 6 Allo-tenuazonic | -4.487 | 2.845 | -3.038 |
Piroxicam | -4.800 | -2.982 | -2.841 |