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Table 2 The combination index (CI) values of the combined extract of mulberry fruit and mulberry leaf and dose reduction index (DRI) value of mulberry fruit extract and mulberry leaf extract

From: The neuroprotective effects of the combined extract of mulberry fruit and mulberry leaf against hydrogen peroxide-induced cytotoxicity in SH-SY5Y Cells

Parameters

EC50 (mg/ml)

Mulberry fruit extract

Mulberry leaf extract

The combined extract of mulberry fruit and mulberry leaf

Combination index

(Type of interaction)

Dose reduction index

Mulberry fruit extract

Mulberry leaf extract

DPPH

151.25 ± 3.36

187.86 ± 3.32

72.73 ± 3.56

0.87 ± 0.02

(synergism)

2.09 ± 0.04

2.59 ± 0.05

FRAP

72.85 ± 0.52

144.90 ± 1.84

63.88 ± 1.27

1.32 ± 0.02

(additive)

1.14 ± 0.02

2.27 ± 0.04

ABTS

106.07 ± 2.97

184.47 ± 1.49

77.18 ± 0.82

0.99 ± 0.01

(synergism)

1.37 ± 0.01

2.39 ± 0.01

COX-II

51.55 ± 0.16

52.62 ± 0.36

48.33 ± 0.20

1.86 ± 0.00

(antagonism)

1.07 ± 0.00

1.09 ± 0.00

  1. Data are presented as mean ± SEM