Table 2 Other indices related to the quality of the RCTs included in this review
Period (Decade) | Number of RCTs | Sample size | Informed consent | Ethics approval | Trial registration | Adverse events |
|---|---|---|---|---|---|---|
mean, median(SD)(min–max) | reported/not mentioned (% reported) | reported/not mentioned(% reported) | reported/not mentioned(% reported) | reported/not mentioned(% reported) | ||
1960s | 1 | 32, 32 (N/A) (N/A) | 0/1 (0%) | 0/1 (0%) | 0/1 (0%) | 0/1 (0%) |
1970s | 6 | 22.7, 20 (6.9) (14–32) | 0/6 (0%) | 0/6 (0%) | 0/6 (0%) | 0/6 (0%) |
1980s | 9 | 37.4, 39 (14.3) (20–60) | 0/9 (0%) | 0/9 (0%) | 0/9 (0%) | 1/8 (10%) |
1990s | 5 | 93.0, 41 (103.0) (26–272) | 2/3 (40%) | 0/5 (0%) | 0/5 (0%) | 0/5 (0%) |
2000s | 40 | 36.8, 28 (31.3) (6–178) | 37/3 (93%) | 24/16 (60%) | 0/40 (0%) | 13/27 (33%) |
2010s | 47 | 36.1, 22 (41.5) (7–210) | 45/2 (96%) | 41/6 (87%) | 4/43 (9%) | 13/34 (28%) |
Total | 108 | 38.3, 29 (40.8) (6–272) | 84/24 (78%) | 65/43 (60%) | 4/104 (4%) | 27/81 (25%) |