Table 3 Fluorescence area and fluorescence intensity in zebrafish livers

Parthenolide

Control

100.00 ± 5.22

100.00 ± 0.89

Celastrol

Control

100.00 ± 0.59

100.00 ± 4.07

7.5 μM

70.46 ± 0.26*

98.21 ± 1.09

0.625 μM

75.61 ± 1.43**

63.89 ± 0.38*

15 μM

78.61 ± 1.94

90.65 ± 1.70*

1.25 μM

(Dead)

(Dead)

30 μM

(Dead)

(Dead)

2.5 μM

(Dead)

(Dead)

Triptolide

Control

100.00 ± 0.35

100.00 ± 3.50

Demethylzeylasteral

Control

100.00 ± 0.59

100.00 ± 4.07

7.5 nM

65.14 ± 2.36**

86.63 ± 0.46

0.625 μM

89.41 ± 3.19

86.49 ± 0.23

15 nM

57.50 ± 3.44**

77.97 ± 1.50*

1.25 μM

72.48 ± 0.28**

77.04 ± 0.15*

30 nM

41.42 ± 3.09**

67.35 ± 4.48*

2.5 μM

(Dead)

(Dead)

Triptonide

Control

100.00 ± 0.59

100.00 ± 4.07

Wilforlide A

Control

100.00 ± 3.61

10.00 ± 1.35

12.5 nM

76.05 ± 2.21**

92.20 ± 4.79

7.5 μM

62.68 ± 0.19**

84.68 ± 0.33**

25 nM

77.24 ± 2.25*

87.90 ± 2.22

15 μM

41.51 ± 1.95**

60.34 ± 4.65*

50 nM

58.31 ± 5.71*

80.95 ± 2.89

30 μM

41.28 ± 0.93**

62.65 ± 4.13*

Triptophenolide

Control

100.00 ± 0.35

100.00 ± 3.50

Triptotriterpenic acid A

Control

100.00 ± 0.83

100.00 ± 0.99

7.5 μM

109.71 ± 0.99

95.82 ± 1.81

7.5 μM

84.50 ± 1.86*

91.81 ± 0.08*

15 μM

(Dead)

(Dead)

15 μM

80.48 ± 3.26*

84.76 ± 1.57*

30 μM

(Dead)

(Dead)

30 μM

83.87 ± 2.47*

87.07 ± 0.49**

Triptobenzene H

Control

100.00 ± 3.61

100.00 ± 1.35

Regelidine

Control

100.00 ± 0.35

100.00 ± 3.50

7.5 μM

63.47 ± 2.88*

73.38 ± 2.39*

7.5 μM

67.22 ± 1.71**

84.22 ± 1.29

15 μM

41.57 ± 1.42**

61.04 ± 2.35**

15 μM

56.00 ± 0.25**

87.71 ± 3.29

30 μM

29.57 ± 3.75**

50.75 ± 1.48**

30 μM

51.36 ± 1.58**

82.11 ± 0.57*

Hypodiolide

Control

100.00 ± 55.22

100.00 ± 3.61

Wilforine

Control

100.00 ± 1.35*

100.00 ± 3.61

7.5 μM

90.68 ± 5.78

93.62 ± 3.95

7.5 μM

78.55 ± 2.35

81.41 ± 5.90

15 μM

95.26 ± 4.42

97.55 ± 1.30

15 μM

76.17 ± 2.62*

78.45 ± 7.02

30 μM

89.99 ± 1.80

89.59 ± 1.37*

30 μM

79.20 ± 1.98*

80.09 ± 6.30