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Table 3 Quantification of FBG, serum insulin, insulin sensitivity, resistance, and beta-cell function in T2DM rats treated with FO and its HF, CF, and EF (200 mg/kg) for 28 days

From: Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway

Groups

FBS (mg/dL)

Serum Insulin (mIU/L)

HOMA-IR

HOMA-B

Insulin sensitivity

Control

83.1 ± 13*

9.24 ± 0.17*

1.59 ± 0.12

44.1 ± 3.45

1.76 ± 1.0

DM Control

270.6 ± 33

7.46 ± 0.06

4.8 ± 0.20

6.82 ± 0.42

0.98 ± 0.02

DM Glic

146.7 ± 98*

11.6 ± 0.48

2.43 ± 0.78*

48.5 ± 18.35*

1.44 ± 0.28*

HF

97.25 ± 29*

11.85 ± 1.61

3.8 ± 2.77

40.2 ± 25.31*

1.27 ± 0.39

EF

105.2 ± 37*

11.12 ± 0.96

5.36 ± 2.09

19.7 ± 11.5

0.96 ± 0.15

CF

182.8 ± 62*

11.15 ± 1.62

3.03 ± 1.06

37.1 ± 17.8*

1.27 ± 0.23

FO

82.3 ± 17*

10.8 ± 0.37*

1.82 ± 0.07*

53.4 ± 1.22*

1.67 ± 0.05*

  1. * shows the significant difference of p-value < 0.05 as compared to DM control