Fig. 4

Administration of C. anthelminticum FO and its fractions alleviate oxidative stress in DN. The percent inhibition of SOD, reduced GSH, GPx, CAT, and HMG-COA: Melvonate ratio except LPO in kidney tissue extracts of different groups. The results are expressed as the mean ± S.E.M. Statistical analysis was carried out using the One-way ANOVA followed by LSD multiple comparisons post-hoc test. Abbreviations: DM-C: DM + 1 mL/kg distilled water, DM-Glic: DM + 200 mg/kg Glicalized, FO: DM + 200 mg/kg C. anthelminticum fixed oil, HF: DM + 200 mg/kg hexane fraction, CF: DM-control + 200 mg/kg chloroform fraction and EF: DM + 200 mg/kg ethanol fraction. *p < 0.05 versus Normal; #p < 0.05 versus DM Control