Fig. 4

The effect of L-carnitine on testicle tissues and spermatogenesis in MSG-induced male rats (n = 10). Control (A), sham (B), and LC 200 (C) groups displayed no histopathological changes, while the MSG group (D) demonstrated degenerative changes in the testis, a reduction in the germinal epithelium height, and loss of sexual lineage cells. In comparison to the MSG group, the MSG + LC 100 group (E) exhibited no significant changes. However, the MSG + LC 200 group (F) showed a significant improvement in MSG-induced structural impairments such as the loss of sexual lineage cells and deformity in the seminiferous tubules in the testis tissue. The seminiferous tubules seemed atrophic, as shown by the thick arrow (hematoxylin and eosin staining at 40 × magnification)