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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Novel mechanism of napabucasin, a naturally derived furanonaphthoquinone: apoptosis and autophagy induction in lung cancer cells through direct targeting on Akt/mTOR proteins

Fig. 5

Molecular docking of NB and PI3K compared to non-isoform-specific PI3K inhibitor (wortmannin). (A) The 3D binding site of NB and wortmannin. (B) PI3K in complexed with wortmannin and PI3K in complexed with NB. The blue dashed lines denoted hydrogen-bonding interaction. Val882 was colored in pink. (C) Docking energy of NB and PI3K compared to wortmannin

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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