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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Novel mechanism of napabucasin, a naturally derived furanonaphthoquinone: apoptosis and autophagy induction in lung cancer cells through direct targeting on Akt/mTOR proteins

Fig. 1

Synthesis of NB and NB-acid and their effects on cell viability in NSCLC cells (H460, H292, H23, and A549), human bronchial epithelial cell line (BEAS-2B), and human endothelial cell line (EA.hy926). (A) Synthesis of NB and NB-acid (B) Structures of NB and NB-acid (C-F) The cells were seeded and treated with 0–100 µM of NB-acid and NB for 24 h. Then, the MTT assay was performed to examine the percentages of cell viability. IC50 of each compounds was calculated compared to the untreated control. Data represent the mean ± SD (n = 3) (* 0.01 ≤ p < 0.05, ** p < 0.01, compared with the untreated control)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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