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Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: Ayurvedic formulations Guduchi and Madhuyashti triggers JNK signaling mediated immune response and adversely affects Huntington phenotype

Fig. 8

Formulation feeding elevated Caspase expression in GMR-GAL4driven 127Q expressing eye discs. Confocal projection images showing larval eye imaginal discs stained with anti-Caspase3 in WT eye imaginal disc (a) or GMR-GAL4 > UAS-127Q/CyO-GFP larval discs when fed on regular food (b) Guduchi (c) or Madhuyashti (d). Nuclei counterstained with DAPI (blue) (e, f, g, h). Scale bar in section A, 50 μm is applicable to all sections from a-h. B Graph represents the mean (±SD) fluorescence intensities of Caspase3 (Y-axis) in different feeding regimes, drawn through LSM 510 Meta. The blue, yellow and green bars represent control, Guduchi and Madhuyashti respectively. ** represents P ≤ 0.001 and * represents P ≤ 0.05 using Student’s t test

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