Table 1 Black Salve constituent 24 hour cytotoxicity analysis
From: Understanding of black salve toxicity by multi-compound cytotoxicity assays
Cell Line | A375 Melanoma | A431 SCC | ||
|---|---|---|---|---|
Compound | IC50 (μM) | S.E. | IC50 (μM) | S.E. |
Sanguinarine | 2.1 | 0.15 | 3.14 | 0.3 |
Chelerythrine | 10.29 | 0.71 | 10.79 | 0.5 |
Sanguilutine | 25.7 | 2.98 | 15.34 | 2.73 |
Chelilutine | 16.15 | 0.33 | 16.5 | 1.04 |
Chelirubine | 11.88 | 1.09 | 14.43 | 0.46 |
Protopine | > 200 |  | > 200 |  |
Allocryptopine | 312.67 | 38.58 | 276.96 | 12.37 |
NDGA | 117.94 | 11.3 | 201.96 | 7.52 |
ZnCl2 | 334.74 | 12.28 | 612.35 | 15.37 |
5-FU | 1046.43 | 77.08 | > 2000 |  |