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Table 5 Effects of bioprocessed Ecklonia cava and its purified products on chemoattractant and eicosanoid releases into BALF from OVA-sensitized/challenged mice

From: Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma

 

Chemoattractants (pg/mL)

Eicosanoids (ng/mL)

eotaxin

VCAM-1

LTC4

PGD2

Vehicle

21.8 ± 2.2e

2.5 ± 0.2d

30.7 ± 2.7d

28.5 ± 1.7d

OVA only

127 ± 12a

28.3 ± 1.9a

105.7 ± 8.3a

82.4 ± 6.3a

EC-1

95.7 ± 5.6 b

20.6 ± 1.7b

81.9 ± 8.2b

65.6 ± 4.8b

EC-2

98.2 ± 7.2b

22.4 ± 1.4b

85.6 ± 8.3b

69.1 ± 5.2b

EC-F-1

62.5 ± 5.4d

11.8 ± 0.8c

61.4 ± 5.7c

50.6 ± 4.2c

EC-F-2

68.9 ± 6.3c

12.5 ± 1.2c

66.3 ± 4.9c

52.8 ± 3.7c

EC-F-3

70.3 ± 5.8c

13.1 ± 1.1c

65.7 ± 4.2c

53.6 ± 4.9c

EC-F-4

70.1 ± 6.9c

12.8 ± 0.9c

64.8 ± 6.2c

55.1 ± 5.1c

  1. Data are shown as the mean ± SD of three independent repetitions. PBS was used as vehicle. Values in each column with the same superscript letters a-e are not significantly different between groups at p < 0.05