Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma

Table 3 Effects of bioprocessed Ecklonia cava and its purified products on total IgE production in U266.B1 human multiple myeloma cells

		IgE concentration (ng/mL)
Vehicle		7.9 ± 1.6^e
Positive control: (10 μg/mL LPS + 5 ng/mL IL-4)		489 ± 52^a
EC-1	1 μg/mL	473 ± 44^a
	10 μg/mL	464 ± 40^a
	100 μg/mL	442 ± 52^ab
EC-2	0.41 μg/mL	466 ± 42^a
	4.1 μg/mL	448 ± 38^ab
	41 μg/mL	433 ± 41^ab
EC-F-1	1 μg/mL	419 ± 36^b
	10 μg/mL	318 ± 33^c
	100 μg/mL	224 ± 29^d
EC-F-2	0.31 μg/mL	408 ± 32^b
	3.1 μg/mL	316 ± 28^c
	31 μg/mL	209 ± 19^d
EC-F-3	0.29 μg/mL	431 ± 36^ab
	2.9 μg/mL	356 ± 31^bc
	29 μg/mL	232 ± 25^d
EC-F-4	0.09 μg/mL	394 ± 42^b
	0.9 μg/mL	308 ± 28^c
	9 μg/mL	194 ± 23^d

Data are shown as the mean ± SD of three independent repetitions. PBS was used as vehicle. Values in each column with the same superscript letters a-e are not significantly different between groups at p < 0.05

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