Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma

Table 2 Inhibitory effect of bioprocessed Ecklonia cava and its purified products on β-hexosaminidase releases stimulated by A23187 in RBL-2H3 cells

		β-hexosaminidase release (%)
Vehicle		0 ± 10^e
Positive control (10 μM calcium ionophore A23187)		100 ± 15^a
EC-1	1 μg/mL	93 ± 12^ab
	10 μg/mL	78.1 ± 4.0^bc
	100 μg/mL	66 ± 10^d
EC-2	0.41 μg/mL	84.4 ± 4.3^b
	4.1 μg/mL	73.0 ± 9.5^c
	41 μg/mL	62.5 ± 7.1^d
EC-F-1	1 μg/mL	91.5 ± 9.7^ab
	10 μg/mL	81.3 ± 3.5^b
	100 μg/mL	76.7 ± 2.3^c
EC-F-2	0.31 μg/mL	95.5 ± 6.0^a
	3.1 μg/mL	87.5 ± 3.5^ab
	31 μg/mL	83.8 ± 4.2^b
EC-F-3	0.29 μg/mL	98.6 ± 7.7^a
	2.9 μg/mL	94.6 ± 3.1^a
	29 μg/mL	90 ± 12^ab
EC-F-4	0.09 μg/mL	102 ± 12^a
	0.9 μg/mL	98.6 ± 3.0^a
	9 μg/mL	94.0 ± 6.8^a

Data are shown as the mean ± SD of three independent repetitions. PBS was used as vehicle. Values in each column with the same superscript letters a-e are not significantly different between groups at p < 0.05

ISSN: 2662-7671