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Table 8 Inhibition of lung metastasis after resection of xenograft tumor in 615 mice

From: Effects of plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/β-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model

Group

Number of mice

Grade of lung metastasis

Total score

Mean rank

IR of pulmonary metastasis (%)

0

I

II

III

Model control

9

0

1

3

5

22

40.22

-

5-Fu

8

2

1

3

2

13

30.19

24.94

Low-dose

12

4

5

1

2

13

24.04*

40.23

Medium-dose

13

7

2

1

3

13

22.31*

44.53

High-dose

11

5

3

1

2

11

22.64*

43.71

  1. *p < 0.05 vs. model control