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Table 3 The effects of E. globulus leaf fractions on body weight and temperature against P.berghei infected mice in the 4-day suppressive test

From: Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice

Treatments

Bodyweight at D0 (g)

Bodyweight at D4 (g)

% Change in body weight

The rectal temperature at D0(°C)

The rectal temperature at D4(°C)

% change in rectal temperature

2%tween80 (10 ml/kg)

25.33 ± 1.43

22.58 ± 1.36

−10.90 ± 1.22

35.40 ± 0.58

32.58 ± 0.53

−7.95 ± 0.38

CQ (25 mg/kg)

26.52 ± 0.70

26.88 ± 0.66

1.45 ± 1.51a3

35.80 ± 0.51

35.95 ± 0.31

0.48 ± 1.00a3

CF (mg/kg) 100

26.50 ± 1.09

24.53 ± 1.04

−7.44 ± 0.47b2

36.48 ± 0.33

34.25 ± 0.57

−6.14 ± 1.10b3

 200

24.17 ± 0.91

22.50 ± 0.83

−6.87 ± 0.92b2

36.35 ± 0.32

34.82 ± 0.48

−4.23 ± 0.55a1b2

 400

24.68 ± 1.23

24.78 ± 1.24

0.44 ± 1.21a3

36.45 ± 0.44

36.17 ± 0.31

−0.74 ± 0.77a3

EAF (mg/kg)100

28.05 ± 0.60

25.85 ± 0.70

−7.90 ± 0.57b3

36.13 ± 0.49

34.03 ± 0.63

−5.84 ± 0.63b3

 200

25.73 ± 1.44

23.65 ± 1.52

−8.29 ± 1.50b3

36.02 ± 0.51

35.03 ± 0.43

−2.71 ± 0.50a1

 400

25.77 ± 1.561.01

25.93 ± 1.29

1.07 ± 2.05a3

36.35 ± 0.55

36.50 ± 0.26

0.48 ± 0.90a3

DW (10 ml/kg)

26.67 ± 1.23

23.97 ± 1.27

−10.24 ± 1.01

36.03 ± 0.42

33.62 ± 0.54

−6.73 ± 0.48

CQ (25 mg/kg)

26.52 ± 0.70

26.88 ± 0.66

1.45 ± 1.51a3

35.80 ± 0.51

35.95 ± 0.31

0.48 ± 1.00a3

AF (mg/kg) 100

26.28 ± 0.88

24.30 ± 0.94

−7.62 ± 0.64b2

36.17 ± 0.39

34.30 ± 0.39

−5.16 ± 0.52b3

 200

27.42 ± 1.01

25.60 ± 0.91

−6.57 ± 1.00b2

35.90 ± 0.35

34.78 ± 0.31

−3.09 ± 0.74a2b1

 400

26.25 ± 0.58

26.08 ± 0.82

−0.62 ± 2.34a3

36.12 ± 0.32

36.17 ± 0.28

0.16 ± 0.72a3

  1. Data are expressed as mean ± SEM
  2. CF Chloroform fraction, EAF Ethyl acetate fraction, DW Distilled water, AF Aqueous fraction, CQ Chloroquine
  3. 1p < 0.05
  4. 2p < 0.01, p < 0.001
  5. acompared to negative controls
  6. bcompared to chloroquine