Antimalarial activity of solvent fractions of a leaf of Eucalyptus globulus labill against Plasmodium berghei infected mice

Table 2 The effects of E. globulus leaf solvent fractions against P. berghei infected mice in the 4-day suppressive test

Treatments	% Parasitemia	% Parasitemia suppression	Mean survival time (day)
2%tween 80 (10 ml/kg)	34.67 ± 2.16	–	9.50 ± 0.99
CQ (25 mg/kg)	0.00 ± 0.00	100.00 ± 0.00^a3	29.50 ± 0.34^a3
CF (mg/kg) 100	17.00 ± 0.89	52.91 ± 3.43^a3b3	16.83 ± 0.95 ^a3b3
200	12.33 ± 0.67	66.08 ± 1.58^a3b3	17.17 ± 0.48^a3b3
400	11.00 ± 0.93	69.93 ± 2.01^a3b3	19.00 ± 1.06^a3b3
EAF (mg/kg) 100	16.00 ± 0.97	53.71 ± 1.64^a3b3	16.00 ± 0.73^a3b3
200	13.67 ± 0.71	60.31 ± 1.66^a3b3	16.17 ± 1.01^a3b3
400	10.83 ± 0.79	68.13 ± 3.05^a3b3	22.50 ± 0.92^a3b3
DW (10 ml/kg)	36.50 ± 1.65	–	9.00 ± 0.73
CQ (25 mg/kg)	0.00 ± 0.00	100.00 ± 0.00^a3	29.50 ± 0.34^a3
AF (mg/kg) 100	26.17 ± 1.01	23.28 ± 5.05^a3b3	10.33 ± 1.02 ^b3
200	22.33 ± 0.95	34.01 ± 5.52^a3b3	12.17 ± 0.75^b3
400	16.83 ± 0.91	50.61 ± 3.83^a3b3	15.67 ± 0.67^a3b3

Data are expressed as mean ± SEM
CF Chloroform fraction, EAF Ethyl acetate fraction, DW Distilled water, AF Aqueous fraction, CQ Chloroquine
¹p < 0.05
²p < 0.01, p < 0.001
^acompared to negative controls
^bcompared to chloroquine

ISSN: 2662-7671