Time | 4W | 8W | 12W | 16W | ||||
---|---|---|---|---|---|---|---|---|
Group | C | M | C | M | C | M | C | M |
Body weight | 23.73±0.93 | 30.93± 1.10** | 27.67± 3.28 | 33.68± 1.08* | 31± 2.26 | 38.8± 0.70* | 31.8± 0.92 | 49.6± 1.09*** |
Liver weight | 1.03± 0.07 | 0.75± 0.06 | 1.18± 0.16 | 1.20± 0.03 | 1.20± 0.01 | 1.30± 0.04 | 1.16± 0.11 | 1.64± 0.17*** |
Serum ALT | 33.0± 3.0 | 32.17± 3.06 | 34.0± 2.29 | 29.17± 0.76 | 33.5± 11.63 | 35.67±5.49 | 29.0± 16.26 | 99.0± 10.04** |
Serum AST | 141.3±25.76 | 155.8± 46.2 | 164.0± 3.78 | 153.0± 40.3 | 162.7± 2.75 | 175.3±6.29 | 157.0±3.54 | 198.3± 24.06 |
Serum TG | 0.82± 0.23 | 0.75± 0.18 | 1.93± 0.28 | 1.55± 0.49 | 1.00± 0.22 | 1.18± 0.21 | 1.43± 0.60 | 0.88± 0.15 |
Serum TC | 1.90± 0.15 | 3.12± 0.25 | 2.60± 0.23 | 5.58± 0.08*** | 2.72± 0.40 | 5.63± 0.43*** | 3.28± 0.46 | 6.28± 0.84*** |
Serum HDL-c | 1.87± 0.21 | 3.10± 0.23 | 2.52± 0.28 | 5.52± 0.24*** | 2.68± 0.43 | 5.60± 0.56*** | 3.58± 0.46 | 6.70± 0.69*** |
Serum LDL-c | 0.23± 0.15 | 0.43± 0.15 | 0.12± 0.03 | 0.67± 0.15* | 0.23± 0.06 | 0.85± 0.13 | 0.30± 0.14 | 1.15± 0.30** |