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Table 2 Effect of genistein on MPO, NF-kB, 4-HNE expression and acinar cell apoptosis in acute pancreatitis mice

From: Genistein attenuated oxidative stress, inflammation, and apoptosis in L-arginine induced acute pancreatitis in mice

Groups (n = 6) Parameters
MPO positive (cells of HPF) NF-kB Positive cells (%) 4-HNE Positive cells (%) TUNEL Positive cells (%)
Con 0.33 ± 0.08 0.44 ± 0.01 0.40 ± 0.02 0.07 ± 0.01
AP 21.00 ± 4.60a1 0.75 ± 0.01a1 0.76 ± 0.01a1 0.22 ± 0.01a1
LG 4.13 ± 0.73b1 0.47 ± 0.01a2,b1 0.45 ± 0.01a2,b1 0.09 ± 0.00a2,b1
HG 2.97 ± 0.44b1 0.46 ± 0.01b1 0.43 ± 0.01b1 0.07 ± 0.00b1
  1. Data are express as mean ± SEM. a1p < 0.01, a2p < 0.05 vs. Con group; b1p < 0.01, b2p < 0.05 vs. AP group
  2. Abbreviations: Con Control group, AP Acute pancreatitis group, LG Low dose of genistein group, HG High dose of genistein group, MPO Myeloperoxidase, NF-kB Nuclear factor-kappa beta, 4-HNE 4-Hydroxynonenal, TUNEL Terminal deoxynucleotidyl transferase dUTP nick end labeling