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Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model

Fig. 2

Wenyang Huazhuo Tongluo Formula can alleviate the structural abnormalities of the pulmonary vessels in the bleomycin-induced SSc mouse model. A The masson stain of lung tissues showed that Wenyang Huazhuo Tongluo Formula and KC7F2 can significantly alleviate the pulmonary vascular fibrosis in SSc mouse models. In additional, Wenyang Huazhuo Tongluo Formula and KC7F2 can significantly reduce the concentration of vWF (B), SELE (C), ICAM-1 (D) and VCAM-1 (E) in serum, which were detected by ELISA. The mean values ± SDwas shown for each bar. * (P < 0.05) or ** (P < 0.01) or *** (P < 0.001) represents significance, ns represents no significance. Original magnification: × 20. BLM: Bleomycin, WYHZTL: Wenyang Huazhuo Tongluo formula

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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