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Table 2 Changes in serum and liver parameters in all groups

From: Probiotics and their beneficial effects on alcohol-induced liver injury in a rat model: the role of fecal microbiota

Parameters

Control

Alcohol

Alcohol + L. plantarum

Alcohol + Mixed strains

p-value

ALT (IU/L)

32.3 ± 1.9

46.5 ± 5.6

28.2 ± 6.4

23.0 ± 2.1

0.04*, 0.009**, 0.001#

AST (IU/L)

152.0 ± 21.0

241.2 ± 11.0

125.5 ± 13.4

125.6 ± 11.8

< 0.001*,**,#

TNF-α (pg/mL)

114.1 ± 2.9

128.6 ± 0.9

115.4 ± 1.5

114.7 ± 1.7

< 0.001*,**,#

IL-6 (pg/mL)

267.8 ± 19.7

342.2 ± 15.8

275.3 ± 27.3

285.8 ± 10.6

0.01*, 0.02**, 0.04#

MDA (nmol/mg protein)

1.34 ± 0.05

1.52 ± 0.04

1.32 ± 0.04

1.38 ± 0.03

0.005*, 0.002**, 0.03#

LPS (EU/mL)

12.9 ± 4.1

27.8 ± 3.0

16.4 ± 3.4

18.8 ± 3.9

0.009*, 0.04**, 0.09#

  1. All parameters are presented as mean ± SD, *p-value between control and alcohol groups, **p-value between alcohol and L. plantarum groups, #p-value between alcohol and mixed strain groups