Parameters | Tissue | Control | CCl4 | Sp150 | Sp300 | Silymarin |
---|---|---|---|---|---|---|
MDA (µmol/L) | Liver | 2.67 ± 0.56 | 7.85 ± 1.66*** | 7.72 ± 1.39 | 3.85 ± 1.49#$ | 6.5 ± 2.05 |
Kidney | 3.21 ± 1.22 | 4.81 ± 0.27* | 4.31 ± 1.14 | 3.27 ± 0.58# | 2.75 ± 1.06## | |
FRAP (µmol/L) | Liver | 938.25 ± 129.54 | 343.4 ± 34.11** | 394 ± 166.46 | 460.33 ± 124.26 | 555.75 ± 21.93# |
Kidney | 1220.75 ± 162.5 | 594.25 ± 73.62* | 1358.33 ± 153.08# | 1218 ± 108.12# | 1164.6 ± 34.68# | |
CAT (µg/g tissue) | Liver | 2.75 ± 0.34 | 1.72 ± 0.37*** | 2.37 ± 0.39# | 2.66 ± 0.2### | 2.37 ± 0.42## |
Kidney | 2.43 ± 0.53 | 1.49 ± 0.21*** | 1.48 ± 0.25 | 2.11 ± 0.23##$ | 2.34 ± 0.27### | |
GSH (µg/g tissue) | Liver | 5.79 ± 2.15 | 3.3 ± 0.61** | 5.1 ± 0.79 | 6.48 ± 0.78### | 5.3 ± 0.67## |
Kidney | 5.66 ± 0.85 | 2.16 ± 0.46*** | 2.91 ± 1.67 | 5.22 ± 0.85###$$ | 7.32 ± 1.23### | |
SOD (nmol/min/ml) | Liver | 8.03 ± 1.1 | 5.95 ± 1.43* | 7.24 ± 0.34 | 8.26 ± 1.86# | 7.22 ± 1.72 |
Kidney | 9.04 ± 2.71 | 6.22 ± 1.51* | 8.16 ± 2.16 | 8.5 ± 1.1 | 7.48 ± 1.04 |