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Table 3 Effects of CCl4 and S. pachycarpa on antioxidant parameters in rat

From: Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats

Parameters

Tissue

Control

CCl4

Sp150

Sp300

Silymarin

MDA (µmol/L)

Liver

2.67 ± 0.56

7.85 ± 1.66***

7.72 ± 1.39

3.85 ± 1.49#$

6.5 ± 2.05

Kidney

3.21 ± 1.22

4.81 ± 0.27*

4.31 ± 1.14

3.27 ± 0.58#

2.75 ± 1.06##

FRAP (µmol/L)

Liver

938.25 ± 129.54

343.4 ± 34.11**

394 ± 166.46

460.33 ± 124.26

555.75 ± 21.93#

Kidney

1220.75 ± 162.5

594.25 ± 73.62*

1358.33 ± 153.08#

1218 ± 108.12#

1164.6 ± 34.68#

CAT (µg/g tissue)

Liver

2.75 ± 0.34

1.72 ± 0.37***

2.37 ± 0.39#

2.66 ± 0.2###

2.37 ± 0.42##

Kidney

2.43 ± 0.53

1.49 ± 0.21***

1.48 ± 0.25

2.11 ± 0.23##$

2.34 ± 0.27###

GSH (µg/g tissue)

Liver

5.79 ± 2.15

3.3 ± 0.61**

5.1 ± 0.79

6.48 ± 0.78###

5.3 ± 0.67##

Kidney

5.66 ± 0.85

2.16 ± 0.46***

2.91 ± 1.67

5.22 ± 0.85###$$

7.32 ± 1.23###

SOD (nmol/min/ml)

Liver

8.03 ± 1.1

5.95 ± 1.43*

7.24 ± 0.34

8.26 ± 1.86#

7.22 ± 1.72

Kidney

9.04 ± 2.71

6.22 ± 1.51*

8.16 ± 2.16

8.5 ± 1.1

7.48 ± 1.04

  1. The data in the table represent the mean ± SD (n = 8). * P < 0.05, ** P < 0.01 and *** P < 0.001 compared to control group. $ P < 0.05 and $$ P < 0.01 indicate the difference between Sp150 group and Sp300 group. # P < 0.05, ## P < 0.01 and ### P < 0.001 indicate the difference between CCl4 group and other groups except the control group