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Table 2 Effects of CCl4 and/or S. pachycarpa on hematological parameters in rat

From: Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats

Parameters

Control

CCl4

Sp150

Sp300

Silymarin

WBC (1000/µL)

7.54 ± 2.37

10.16 ± 2.65

8.6 ± 0.52

7.33 ± 1.75

5.92 ± 0.86

RBC (Mil/µ)

8.31 ± 0.29

6.62 ± 0.6***

8.09 ± 0.61##

8.23 ± 0.55###

8.16 ± 0.31###

Hb (g/dL)

14.02 ± 0.38

12 ± 0.79***

13.86 ± 0.41##

14.13 ± 0.77###

13.4 ± 0.45#

HCT (%)

43.21 ± 1.29

41.18 ± 6.08

44.3 ± 1.22

43.8 ± 2.8

41.97 ± 1.88

MCV (fL)

52 ± 2.16

45 ± 5.46*

50.53 ± 4.14

51.86 ± 3.32

51.42 ± 1.48

MCH (pg)

16.87 ± 0.42

15.74 ± 0.85*

16.83 ± 0.7

16.83 ± 0.25

16.45 ± 0.23

MCHC (g/dL)

32.44 ± 0.73

29.58 ± 2.28

31.43 ± 4

31.8 ± 3.24

31.92 ± 0.6

Plt (1000/µL)

746.29 ± 251.13

392.2 ± 150.38*

680.67 ± 151.43

641.33 ± 126.95

762.5 ± 239.19

Neutrophils (%)

32.6 ± 11.54

48.84 ± 6.6

44.9 ± 8.19

36.6 ± 12.68

36.47 ± 15.36

Lymphocyte (%)

59.32 ± 8.89

50.52 ± 12.28

43.3 ± 5.11

39.33 ± 9.5

58.4 ± 17.25

Monocyte (%)

4.82 ± 2.58

6.92 ± 1.9

7.26 ± 1.8

7.43 ± 2.83

7.05 ± 1.16

Eosinophil (%)

3.24 ± 1.4

3.9 ± 1.83

4.53 ± 1.98

2.13 ± 1.81

3.25 ± 1.41

  1. Data are means ± SD (n = 8). * P < 0.05, ** P < 0.01 and *** P < 0.001 compared to control group. # P < 0.05, ## P < 0.01 and ### P < 0.001 indicate the difference between CCl4 group and other groups except the control group