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Table 1 Effects of CCl4 and/or S. pachycarpa on serum biochemical parameters in rat

From: Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats

Parameters

Control

CCl4

Sp150

Sp300

Silymarin

SGOT (AST) (IU/L)

113.29 ± 17.52

545 ± 99.24***

488.67 ± 219.32

239 ± 33.71##

249.71 ± 143.77##

SGPT (ALT) (IU/L)

66 ± 12.97

646 ± 151.38***

456.33 ± 275.95

278 ± 42.03##

273.67 ± 167.74##

ALP (U/L)

232.57 ± 39.64

443.4 ± 193.92*

389.66 ± 67.21

254 ± 96.23#

320.85 ± 159.28

FBS (mg/dL)

138.14 ± 9.78

240 ± 66.52**

194.67 ± 17.95

184.67 ± 12.22#

156.43 ± 35.2##

Cholesterol (mg/dL)

124 ± 3

223.8 ± 23.34**

139.66 ± 15.14#

130.66 ± 8.32#

140 ± 38.94#

TG (mg/dL)

91.29 ± 14.2

104.8 ± 39.96

90 ± 47.28

103.66 ± 8.32

94.43 ± 25.57

HDL (mg/dL)

70.86 ± 13.01

65 ± 10.63

71.67 ± 7.37

60.33 ± 6.5

63 ± 10.29

LDL (mg/dL)

42 ± 11.91

79.4 ± 9.04***

48.67 ± 17.01##

42.33 ± 8.08###

46.43 ± 12.96###

VLDL (mg/dL)

18.14 ± 2.61

21.4 ± 6.87

18 ± 9.64

20.33 ± 2.3

16 ± 7.14

Creatinine (mg/dL)

0.86 ± 0.07

1.36 ± 0.28**

0.94 ± 0.23

0.95 ± 0.1#

0.91 ± 0.18#

Urea (mg/dL)

58.29 ± 12.27

83.6 ± 23.79*

75.67 ± 6.42

69.33 ± 6.65

71.14 ± 26.78

BUN (mg/dL)

27.22 ± 5.75

45.56 ± 13.37**

35.4 ± 8.31

35.36 ± 3

33.3 ± 1.46#

Uric Acid (mg/dL)

0.6 ± 0.21

2.32 ± 0.37***

1.11 ± 0.72#

1.31 ± 0.87

1.82 ± 0.56

  1. The data in the table represent the mean ± SD (n = 8). * P < 0.05, ** P < 0.01 and *** P < 0.001 compared to control group. # P < 0.05, ## P < 0.01 and ### P < 0.001 indicate the difference between CCl4 group and other groups except the control group