Parameters | Control | CCl4 | Sp150 | Sp300 | Silymarin |
---|---|---|---|---|---|
SGOT (AST) (IU/L) | 113.29 ± 17.52 | 545 ± 99.24*** | 488.67 ± 219.32 | 239 ± 33.71## | 249.71 ± 143.77## |
SGPT (ALT) (IU/L) | 66 ± 12.97 | 646 ± 151.38*** | 456.33 ± 275.95 | 278 ± 42.03## | 273.67 ± 167.74## |
ALP (U/L) | 232.57 ± 39.64 | 443.4 ± 193.92* | 389.66 ± 67.21 | 254 ± 96.23# | 320.85 ± 159.28 |
FBS (mg/dL) | 138.14 ± 9.78 | 240 ± 66.52** | 194.67 ± 17.95 | 184.67 ± 12.22# | 156.43 ± 35.2## |
Cholesterol (mg/dL) | 124 ± 3 | 223.8 ± 23.34** | 139.66 ± 15.14# | 130.66 ± 8.32# | 140 ± 38.94# |
TG (mg/dL) | 91.29 ± 14.2 | 104.8 ± 39.96 | 90 ± 47.28 | 103.66 ± 8.32 | 94.43 ± 25.57 |
HDL (mg/dL) | 70.86 ± 13.01 | 65 ± 10.63 | 71.67 ± 7.37 | 60.33 ± 6.5 | 63 ± 10.29 |
LDL (mg/dL) | 42 ± 11.91 | 79.4 ± 9.04*** | 48.67 ± 17.01## | 42.33 ± 8.08### | 46.43 ± 12.96### |
VLDL (mg/dL) | 18.14 ± 2.61 | 21.4 ± 6.87 | 18 ± 9.64 | 20.33 ± 2.3 | 16 ± 7.14 |
Creatinine (mg/dL) | 0.86 ± 0.07 | 1.36 ± 0.28** | 0.94 ± 0.23 | 0.95 ± 0.1# | 0.91 ± 0.18# |
Urea (mg/dL) | 58.29 ± 12.27 | 83.6 ± 23.79* | 75.67 ± 6.42 | 69.33 ± 6.65 | 71.14 ± 26.78 |
BUN (mg/dL) | 27.22 ± 5.75 | 45.56 ± 13.37** | 35.4 ± 8.31 | 35.36 ± 3 | 33.3 ± 1.46# |
Uric Acid (mg/dL) | 0.6 ± 0.21 | 2.32 ± 0.37*** | 1.11 ± 0.72# | 1.31 ± 0.87 | 1.82 ± 0.56 |