Fig. 1

CSR suppressed hyperproliferation of IL-6/sIL-6R-stimulated RA-FLS. (a) Cell viability determined using CCK-8 assays. Viability of IL-6/sIL-6R plus CSR solvent-treated cells was regarded as 100%. Data from three independent experiments are presented as mean ± SD. * P < 0.05, ** P < 0.01 vs. IL-6/sIL-6R plus CSR solvent-treated group of corresponding treatment duration. (b) Cell proliferation determined using crystal violet staining. Representative photographs of viable cells are shown in the upper panel and quantitative results are shown in the lower panel. Data are expressed as mean ± SD of 3 independent experiments. * P < 0.05, ** P < 0.01 vs. IL-6/sIL-6R plus CSR solvent-treated group