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Table 4 Screening of the minimal inhibitory concentration (MIC) of Vitex agnus-castus extract (µg/ml) by measuring the inhibition zone diameter (mm) for Candida strains

From: Evaluation of anticandidal activities and phytochemical examination of extracts prepared from Vitex agnus-castus: a possible alternative in treating candidiasis infections

Strains

Aqueous extract

p value

MIC

Ethanolic extract

p value

MIC

Methanolic extract

p value

MIC

 + C

25

50

100

200

25

50

100

200

25

50

100

200

C. albicans

-

-

-

10.5

0.87

150

-

-

-

9.5

0.87

150

-

-

-

10

1.00

150

10

C. auris

-

-

-

11

1.00

150

-

-

-

12

0.76

150

-

-

-

10

0.76

150

11

C. dublinesis

-

-

-

11

0.42

150

-

-

-

11

0.42

150

-

-

-

10

0.29

150

14

C. famata

-

-

14

15

0.71

75

-

-

23.5

28.5

0.003*

75

-

-

26.5

30

0.0009*

75

16.5

C. rhodotorula

-

-

-

9

0.10

150

-

-

-

11.5

0.31

150

-

-

-

10

0.16

150

15.5

C. tropicalis

-

-

-

13

0.33

150

-

-

-

11

0.15

150

-

-

-

12

0.23

150

17

C. krusei (ck1)

-

-

14

15.5

0.03*

75

-

-

-

12

0.32

150

-

-

-

15

0.04*

150

9

C. krusei (ck2)

-

-

13

14.5

0.04*

75

-

-

-

12

0.32

150

-

-

-

13

0.18

150

9

C. krusei (ck3)

-

-

15

18

0.71

75

-

-

-

12.5

0.32

150

-

-

-

12.5

0.32

150

16.5

C. parapsilosis (cp1)

-

-

18

20

0.07

75

-

-

-

15

0.01*

150

-

-

-

17

0.02*

150

30

C. parapsilosis (cp2)

-

-

16

18.5

0.26

75

-

-

-

14

0.04*

150

-

-

-

10

0.004*

150

24

  1. (-); no inhibition was noticed. + C; Terbinafine
  2. *P value was calculated by Chi square test against + C