Fig. 2

Effect of AE and NDGA on glucose-treated macrophage proliferation and viability. A, B Effect of glucose on cell proliferation and viability. C Effect of AE on the proliferation of cells treated with glucose. D Effect of NDGA on the proliferation of cells treated with glucose. Cells were incubated for 24 h in the presence of the different concentrations of glucose: 5.5 mM (basal), 11 mM, 55 mM and 110 mM with or without AE or NDGA. The percentage of reversal is indicated over the bars. Results are expressed as the Mean ± SEM of three or more experiments performed in triplicate. * p <0.05, ** <0.01, *** <0.001: significantly different with respect to basal conditions (5.5 mM glucose) and #p < 0.05,## p < 0.01, ###<0.001: significantly different with respect to each glucose concentration (One way ANOVA followed by Dunnett’s test)