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Table 9 Effect of GlucoMedix® on cholesterol levels of normal and hyperlipidemic rats

From: GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome

Group/dose (mg/kg)

Basal

Post-induction

21 days

Control (uninduced)

48.05 ± 0.64

49.12 ± 0.41

65.37 ± 0.87

Negative Control (induced)

51.94 ± 0.53

261.48 ± 13.33

312.31 ± 8.36 **

Atorvastatin 20

50.86 ± 1.13

264.02 ± 14.94

93.48 ± 6.17 * &&

Glucomedix 250

53.63 ± 0.72

259.89 ± 18.89

184.28 ± 5.58 ** &

Glucomedix 500

52.29 ± 1.04

267.61 ± 11.02

146.83 ± 5.96 * &

Glucomedix 1000

49.91 ± 0.98

268.01 ± 8.61

104.56 ± 4.87 * &&

  1. Values are expressed in mg/dl as mean ± SD. n = 5. * p < 0.05, ** p < 0.001 compared to control group; & p < 0.05, && p < 0.001 compared to negative control