GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome

Table 6 Clinical chemistry of male rats treated with GlucoMedix® at 28 days

Group/dose (mg/kg)	GLU (mg/dL)	T-Chol (mg/dL)	TG (mg/dL)	AST(U/L)	ALT(U/L)	BUN (mg/dL)	Crea (mg/dL)	TSH (mIU/L)	T3(mIU/L)	T4(ug/dL)
250	92.2 + 2.59	97.2 + 1.64	70.0 + 1.58	31.4 + 0.89	34.8 + 0.84	37.6 + 2.07	0.84 + 0.17	2.98 + 0.32	2.88 + 0.15	1.14 + 0.15
1000	90.4 + 1.52	92.8 + 4.15	67.4 + 1.52	29.4 + 1.14	33.2 + 2.59	37.2 + 1.64	0.64 + 0.11	2.88 + 0.31	2.68 + 0.16	1.02 + 0.13
2000	87.2 + 2.59	90.8 + 3.56	64.6 + 2.70	27.6 + 2.97	32.8 + 1.64	34.6 + 2.61	0.66 + 0.15	2.88 + 0.43	2.34 + 0.17	0.94 + 0.11
Control	90.0 + 1.58	94.2 + 3.19	65.4 + 3.51	28.2 + 2.86	35.2 + 2.77	35.6 + 3.36	0.80 + 0.07	2.82 + 0.41	2.44 + 0.18	1.04 + 0.13

Values are expressed as mean ± SD. n = 5. Parameters included: glucose (GLU), total cholesterol (T-Chol), triglycerides (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), creatinine (Crea), thyroid stimulating hormone (TSH), and thyroid hormones (T3, T4). No significant difference between the parameters compared to the control group

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