Evaluation of the antidiarrheal activity of 80% methanol extract and solvent fractions of the leaf of Bersama abyssinica fresen (Melianthaceae) in mice

Table 4 In Vivo ADI of crude extract and solvent fractions of the leaves of B. abyssinica

Groups	Dfreq (%)	Gmeq ( %)	Pfreq (%)	ADI (%)
Crude extract (mg/kg)
100	18.75	22.00	15.60	18.06
200	41.67	25.26	40.00	33.58
400	59.89	31.11	62.27	46.91
AF (mg/kg)
100	26.30	21.83	13.33	19.13
200	35.94	29.49	40.00	33.65
400	63.28	32.83	60.00	48.04
CF (mg/kg)
100	20.16	7.69	15.6	13.08
200	33.33	16.10	28.93	24.16
400	63.30	37.22	53.33	48.16
NHF(mg/kg)
100	3.36	6.13	13.33	6.38
200	4.39	10.01	15.6	8.63
400	13.18	35.89	17.33	19.57
Positive control
	83.72	45.49	66.67	60.75

Dfreq Delay in the onset of diarrhea, Gmeq reduction in intestinal transit, Pfreq reduction in the number of wet stools

ISSN: 2662-7671