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Table 4 In Vivo ADI of crude extract and solvent fractions of the leaves of B. abyssinica

From: Evaluation of the antidiarrheal activity of 80% methanol extract and solvent fractions of the leaf of Bersama abyssinica fresen (Melianthaceae) in mice

Groups Dfreq (%) Gmeq ( %) Pfreq (%) ADI (%)
Crude extract (mg/kg)
 100 18.75 22.00 15.60 18.06
 200 41.67 25.26 40.00 33.58
 400 59.89 31.11 62.27 46.91
AF (mg/kg)
 100 26.30 21.83 13.33 19.13
 200 35.94 29.49 40.00 33.65
 400 63.28 32.83 60.00 48.04
CF (mg/kg)
 100 20.16 7.69 15.6 13.08
 200 33.33 16.10 28.93 24.16
 400 63.30 37.22 53.33 48.16
NHF(mg/kg)
 100 3.36 6.13 13.33 6.38
 200 4.39 10.01 15.6 8.63
 400 13.18 35.89 17.33 19.57
Positive control
  83.72 45.49 66.67 60.75
  1. Dfreq Delay in the onset of diarrhea, Gmeq reduction in intestinal transit, Pfreq reduction in the number of wet stools