Skip to main content

Table 3 Effects of crude extract and solvent fractions of the leaves of B. abyssinica on intestinal motility

From: Evaluation of the antidiarrheal activity of 80% methanol extract and solvent fractions of the leaf of Bersama abyssinica fresen (Melianthaceae) in mice

Types of treatment The total length of the intestine (cm) Length of intestine marked with charcoal (cm) PI (%) Inhibition of motility (%)
NEC 57.58 ± 0.87 33.75 ± 1.57 58.76 ± 3.26 –––––––-
Atropine 5 mg/kg 58.50 ± 0.80 18.75 ± 1.57 32.03 ± 2.62 45.49
Crude extract (mg/kg)
 100 59.83 ± 1.72 27.25 ± 1.67b1 45.83 ± 3.48b1 22.00
 200 57.5 ± 0.61 25.17 ± 1.81a1 43.92 ± 3.54a1 25.26
 400 57.73 ± 0.95 23.33 ± 1.76a2 40.48 ± 3.17a2 31.11
AF (mg/kg)
 100 55.92 ± 0.72 25.67 ± 1.08a2b1 45.93 ± 1.97a1b2 21.83
 200 56.42 ± 1.00 23.33 ± 1.26a3 41.43 ± 2.39a2 29.49
 400 57.00 ± 0.76 22.42 ± 1.34a3 39.47 ± 2.82a3 32.83
CF (mg/kg)
 100 57.75 ± 1.24 31.33 ± 1.42 b3e2 54.24 ± 2.06b3e2 7.69
 200 57.92 ± 1.36 28.67 ± 2.00b2 49.30 ± 2.67b3 16.10
 400 57.67 ± 2.46 21.33 ± 1.60a3c2 36.89 ± 1.89a3c2 37.22
NHF (mg/kg)
 100 57.83 ± 1.07 31.83 ± 1.49 b3e2 55.16 ± 2.86 b3e2 6.13
 200 57.17 ± 1.12 30.08 ± 1.65b3e1 52.88 ± 3.32b2e1 10.01
 400 58.08 ± 0.98 21.75 ± 1.53a3c2d1 37.67 ± 3.30a2c2d1 35.89
  1. Results are expressed as mean ± SEM (n = 6); statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. acompared to negative control, bcompared to atropine, ccompared to 100 mg/kg, dcompared to 200 mg/kg, ecompared to 400 mg/kg. 1p < 0.05, 2p < 0.01, 3p < 0.001.NC Negative control