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Table 1 Effects of leaf and bark extracts of Albizia procera on carrageenan-induced paw edema and percentage inhibitions

From: Analgesic, anti-inflammatory and acute oral toxicity profile of leaf and bark extracts of Albizia procera

Group

Treatment

Paw edema [% Inhibition]

0.5 h

1 h

2 h

3 h

5 h

I

Positive control

0.48 ± 0.06

0.60 ± 0.07

0.72 ± 0.08

0.82 ± 0.07

0.84 ± 0.08

II

Diclofenac (25 mg/kg)

0.20 ± 0.03**

[59.50]

0.19 ± 0.03**

[68.39]

0.20 ± 0.02**

[71.87]

0.25 ± 0.05**

[69.49]

0.29 ± 0.06**

[65.27]

III

EALE (100 mg/kg)

0.34 ± 0.04

[29.55]

0.35 ± 0.03*

[41.76]

0.37 ± 0.05**

[48.75]

0.63 ± 0.08

[23.04]

0.73 ± 0.10

[12.22]

IV

EALE (200 mg/kg)

0.30 ± 0.02

[38.02]

0.40 ± 0.03

[34.28]

0.46 ± 0.04*

[36.35]

0.54 ± 0.06

[34.07]

0.55 ± 0.07

[34.61]

V

ETLE (100 mg/kg)

0.27 ± 0.06

[43.80]

0.34 ± 0.03*

[44.09]

0.37 ± 0.04**

[48.19]

0.50 ± 0.04*

[38.73]

0.63 ± 0.11

[24.79]

VI

ETLE (200 mg/kg)

0.20 ± 0.02**

[58.68]

0.20 ± 0.02**

[66.72]

0.21 ± 0.03**

[70.89]

0.33 ± 0.04**

[59.07]

0.46 ± 0.03**

[44.43]

VII

HALE (100 mg/kg)

0.28 ± 0.02

[41.94]

0.38 ± 0.03

[37.27]

0.44 ± 0.03*

[39.14]

0.64 ± 0.05

[21.20]

0.60 ± 0.05

[28.14]

VIII

HALE (200 mg/kg)

0.35 ± 0.05

[28.10]

0.39 ± 0.04

[35.44]

0.45 ± 0.07*

[36.77]

0.61 ± 0.08

[25.61]

0.69 ± 0.08

[17.60]

IX

EABE (100 mg/kg)

0.41 ± 0.07

[15.29]

0.50 ± 0.04

[16.97]

0.71 ± 0.01

[0.97]

0.81 ± 0.03

[0.61]

0.83 ± 0.04

[0.12]

X

EABE (200 mg/kg)

0.48 ± 0.06

[0.83]

0.52 ± 0.04

[13.31]

0.67 ± 0.06

[6.13]

0.81 ± 0.05

[0.25]

0.83 ± 0.05

[1.20]

XI

ETBE (100 mg/kg)

0.23 ± 0.02**

[52.89]

0.28 ± 0.03**

[53.41]

0.31 ± 0.04**

[57.38]

0.36 ± 0.04**

[56.13]

0.36 ± 0.03**

[56.65]

XII

ETBE (200 mg/kg)

0.17 ± 0.03**

[65.29]

0.18 ± 0.03**

[70.05]

0.21 ± 0.03**

[70.47]

0.22 ± 0.02**

[72.79]

0.27 ± 0.01**

[67.90]

XIII

HABE (100 mg/kg)

0.41 ± 0.04

[16.12]

0.58 ± 0.11

[3.99]

0.71 ± 0.03

[0.97]

0.80 ± 0.08

[2.57]

0.83 ± 0.05

[0.12]

XIV

HABE (200 mg/kg)

0.31 ± 0.03

[36.27]

0.41 ± 0.08

[31.45]

0.65 ± 0.10

[9.19]

0.80 ± 0.08

[1.84]

0.83 ± 0.04

[0.96]

  1. Data were expressed as the standard error of the mean (± SEM). n = 6 rats per group. The statistical significance was analyzed by using one way ANOVA followed by Tukey’s multiple comparison tests. Here the symbol ‘*’, and ‘**’ indicates p-value <0.05 and p < 0.01 respectively when compared to the positive control group
  2. Abbreviations: EABE ethyl acetate bark extract, EALE ethyl acetate leaf extract, ETBE ethanolic bark extract, ETLE ethanolic leaf extract, HABE hydro-alcoholic bark extract and HALE hydro-alcoholic leaf extract