Group | Treatment | Paw edema [% Inhibition] | ||||
---|---|---|---|---|---|---|
0.5 h | 1 h | 2 h | 3 h | 5 h | ||
I | Positive control | 0.48 ± 0.06 | 0.60 ± 0.07 | 0.72 ± 0.08 | 0.82 ± 0.07 | 0.84 ± 0.08 |
II | Diclofenac (25 mg/kg) | 0.20 ± 0.03** [59.50] | 0.19 ± 0.03** [68.39] | 0.20 ± 0.02** [71.87] | 0.25 ± 0.05** [69.49] | 0.29 ± 0.06** [65.27] |
III | EALE (100 mg/kg) | 0.34 ± 0.04 [29.55] | 0.35 ± 0.03* [41.76] | 0.37 ± 0.05** [48.75] | 0.63 ± 0.08 [23.04] | 0.73 ± 0.10 [12.22] |
IV | EALE (200 mg/kg) | 0.30 ± 0.02 [38.02] | 0.40 ± 0.03 [34.28] | 0.46 ± 0.04* [36.35] | 0.54 ± 0.06 [34.07] | 0.55 ± 0.07 [34.61] |
V | ETLE (100 mg/kg) | 0.27 ± 0.06 [43.80] | 0.34 ± 0.03* [44.09] | 0.37 ± 0.04** [48.19] | 0.50 ± 0.04* [38.73] | 0.63 ± 0.11 [24.79] |
VI | ETLE (200 mg/kg) | 0.20 ± 0.02** [58.68] | 0.20 ± 0.02** [66.72] | 0.21 ± 0.03** [70.89] | 0.33 ± 0.04** [59.07] | 0.46 ± 0.03** [44.43] |
VII | HALE (100 mg/kg) | 0.28 ± 0.02 [41.94] | 0.38 ± 0.03 [37.27] | 0.44 ± 0.03* [39.14] | 0.64 ± 0.05 [21.20] | 0.60 ± 0.05 [28.14] |
VIII | HALE (200 mg/kg) | 0.35 ± 0.05 [28.10] | 0.39 ± 0.04 [35.44] | 0.45 ± 0.07* [36.77] | 0.61 ± 0.08 [25.61] | 0.69 ± 0.08 [17.60] |
IX | EABE (100 mg/kg) | 0.41 ± 0.07 [15.29] | 0.50 ± 0.04 [16.97] | 0.71 ± 0.01 [0.97] | 0.81 ± 0.03 [0.61] | 0.83 ± 0.04 [0.12] |
X | EABE (200 mg/kg) | 0.48 ± 0.06 [0.83] | 0.52 ± 0.04 [13.31] | 0.67 ± 0.06 [6.13] | 0.81 ± 0.05 [0.25] | 0.83 ± 0.05 [1.20] |
XI | ETBE (100 mg/kg) | 0.23 ± 0.02** [52.89] | 0.28 ± 0.03** [53.41] | 0.31 ± 0.04** [57.38] | 0.36 ± 0.04** [56.13] | 0.36 ± 0.03** [56.65] |
XII | ETBE (200 mg/kg) | 0.17 ± 0.03** [65.29] | 0.18 ± 0.03** [70.05] | 0.21 ± 0.03** [70.47] | 0.22 ± 0.02** [72.79] | 0.27 ± 0.01** [67.90] |
XIII | HABE (100 mg/kg) | 0.41 ± 0.04 [16.12] | 0.58 ± 0.11 [3.99] | 0.71 ± 0.03 [0.97] | 0.80 ± 0.08 [2.57] | 0.83 ± 0.05 [0.12] |
XIV | HABE (200 mg/kg) | 0.31 ± 0.03 [36.27] | 0.41 ± 0.08 [31.45] | 0.65 ± 0.10 [9.19] | 0.80 ± 0.08 [1.84] | 0.83 ± 0.04 [0.96] |