Fig. 5

Comparison of predicted KEGG pathway between NC, Sham and TPEE groups using PICRUSt. The proportion of sequences of NC versus Sham (A), Sham versus TPEE (B), and NC versus TPEE (C). The box plot represents the distribution of the relative abundance of gut microbiome in TPEE and NC groups based on the predicted functional biomarkers associated with inflammatory bowel disease (IBD) and peroxisome proliferator-activated receptor (PPAR) signalling pathways (D). The box plot presented the median with the maximum and minimum values corrected by p < 0.05 determined by Kruskal-Wallis H-test with Benjamin-Hochberg correction